TotalView exists entirely within the File system of the Windows System. Windows Defender is the Default File system anti-virus and anti malware application installed by default on the Windows OS (Server and Desktop). Windows Defender or other applications scanning and locking TotalView files can greatly effect performance of the TotalView Application.
Take into consideration your companies security policies and apply the exclusions appropriately.
Below are the PowerShell Commands to Exclude TotalView Directories, Applications and files
PowerShell must be run with Elevated Privilege to run the commands correctly (Right Click->Run as Administrator)
Folder to Exclude from Scanning
Add-MpPreference -ExclusionPath "C:\Program Files (x86)\PathSolutions\TotalView"
Add-MpPreference -ExclusionPath "C:\Program Files (x86)\PathSolutions\TotalView\Data"
Applications to Exclude from Scanning
TotalView Application (Service)
Add-MpPreference -ExclusionProcess "C:\Program Files (x86)\PathSolutions\TotalView\MonitorSvc.exe"
TotalView Config Tool
Add-MpPreference -ExclusionProcess "C:\Program Files (x86)\PathSolutions\TotalView\MonitorConfig.exe"
TotalView Quick Config Wizard
Add-MpPreference -ExclusionProcess "C:\Program Files (x86)\PathSolutions\TotalView\MonitorWizard.exe"
TotalView NetFlow Analysis Tool
Add-MpPreference -ExclusionProcess "C:\Program Files (x86)\PathSolutions\TotalView\NetflowAnalysisTool.exe"
TotalView Device Configuration Wizard
Add-MpPreference -ExclusionProcess "C:\Program Files (x86)\PathSolutions\TotalView\DeviceConfigWizard.exe"
Files to Exclude from Scanning in the \Data folder
SQLite Database Files
Add-MpPreference -ExclusionExtension ".db"
Add-MpPreference -ExclusionExtension ".db-wal"
Add-MpPreference -ExclusionExtension ".db-shm"
Add-MpPreference -ExclusionExtension ".dat"
Replace the File Path with the correct file path if TotalView is installed in another directory
If you are using tools other than Defender (I.E. Cloud Strike, Cortex, Sentinel One, etc..) please make similar exceptions